Four-year visual, refractive, and contrast sensitivity outcomes after wavefront-guided myopic LASIK using an advanced excimer laser platform.

PURPOSE To evaluate the 4-year visual, refractive, and contrast sensitivity outcomes of wavefront-guided LASIK for the correction of low to moderate myopia using the VISX CustomVue technology (Abbott Medical Optics, Inc., Santa Ana, CA). METHODS This was a prospective study including 255 consecutive eyes of 145 patients (age range: 19 to 55 years) with low to moderate myopia (mean spherical equivalent: -3.36 ± 1.71 diopters [D]) undergoing laser refractive surgery. Wavefront-guided LASIK was performed in all eyes using the VISX STAR S4 IR excimer laser platform and the CustomVue procedure for the ablation profile design. Visual, refractive, and contrast sensitivity changes were evaluated during a 4-year follow-up period. RESULTS Postoperative logMAR uncorrected distance visual acuity was 0.1 or better (20/25 Snellen) in 98.0% and 100% of eyes at 1 and 4 years, respectively. At 4 years postoperatively, mean spherical equivalent was reduced significantly to a mean value of -0.22 ± 0.28 D (P < .01), with 97.3% of eyes with a spherical equivalent within ±0.50 D. The astigmatic power vector component J0 of manifest refraction was also reduced significantly (P < .01). Postoperative logMAR corrected distance visual acuity was 0.0 or better (20/20 Snellen) in 96.1% and 98.8% of eyes at 1 and 4 years, respectively. Improvement in contrast sensitivity was observed in some spatial frequencies between 1 and 4 years postoperatively. No significant correlations were found between 4-year contrast sensitivity and corrected distance visual acuity (0.024 ≤ r ≤ -0.120, P ≥ .06). CONCLUSION Wavefront-guided LASIK using the VISX CustomVue technology provides an effective and predictable correction of low to moderate myopia in the long term, preserving the patient's visual acuity and quality.